Tuesday, October 3, 2017

Brain Changes and Plasticity Probed at Neuronal Level

A recent study provides researchers new information on how sleep helps the brain change and reorganize itself.

Researchers at the Humboldt and Charité Universities in Berlin, Germany, recorded activity in the dendrites of neurons, the tree-like branching structures that propagate electrochemical impulses.

The study, published in Nature Communications, found that activity in dendrites increases when we sleep, and that this increase is linked to specific brain waves that are seen to be key to how we form memories.

Dr. Julie Seibt, Lecturer in Sleep and Plasticity at the University of Surrey and lead author of the study, said, “Our brains are amazing and fascinating organs — they have the ability to change and adapt based on our experiences. It is becoming increasingly clear that sleep plays an important role in these adaptive changes. Our study tells us that a large proportion of these changes may occur during very short and repetitive brain waves called spindles.

“Sleep spindles have been associated with memory formation in humans for quite some time but nobody knew what they were actually doing in the brain. Now we know that during spindles, specific pathways are activated in dendrites, maybe allowing our memories to be reinforced during sleep.

“In the near future, techniques that allow brain stimulation, such as transcranial magnetic stimulation (TMS), could be used to stimulate dendrites with the same frequency range as spindles. This could lead to enhance cognitive functions in patients with learning and memory disorders, such as dementia.”

Source: University of Surrey



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